Surprise finding sheds light on what causes Huntington's disease, a devastating fatal brain disorder
Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the brain to break down and die.
Study finds surprising way that genetic mutation causes Huntington's disease, transforming understanding of the disorder
Scientists have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the understanding of the fatal neurodegenerative disorder and suggest potential ways to delay or even prevent it.
New findings shed light on cause of Huntington's disease progression
A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time, but doesn't start causing harm until it hits a toxic threshold that rapidly leads to the nerve cell’s death.
Early brain changes in Huntington’s disease detected two decades before symptoms
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's disease,
New Research Uncovers Delayed Effects of Genetic Mutation in Huntington's Disease Development
Recent findings uncover how Huntington's disease develops over time, revealing the mutation's delayed effects on brain cells.
Surprise finding sheds light on what causes Huntington’s disease, a devastating fatal brain disorder
Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...
Study Unveils Surprising Cause of Brain Cell Death in Huntington's Disease
Scientists at the Broad Institute of MIT and Harvard, Harvard Medical School, and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells.
New Research Sheds Light on the Causes of Huntington’s Disease
If you’ve ever heard of Huntington’s disease, you know how devastating it can be. This hereditary brain disorder slowly robs people of their ability to think, move, and even communicate. The disease’s progression is relentless,
Science Daily7h
Brain changes in Huntington's disease decades before diagnosis will guide future prevention trials
Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's ...
Harvard Medical School2d
New Understanding of How Genetic Mutation Causes Huntington’s Disease
Study explains long-standing question of why Huntington’s disease symptoms typically do not appear until midlife even though ...
STAT3d
Studies reveal a new biology of Huntington’s, renewing drugmaker interest in therapies
The field of Huntington’s disease research has been undergoing a radical reshaping of how the brain-ravaging disease — and what drives it — is understood. After decades focused on the notion ...
Experts hail 'milestone' in study of the deadly Huntington's disease
About 2,000 people in Australia are affected by Huntington's disease, a fatal and incurable condition that affects the ...
USA Today3d
Medical mystery solved: Why do some people develop Huntington's earlier than others?
CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who ...
C&EN1d
DNA repeat expansion drives Huntington’s development
Studies of living participants and postmortem brains confirm that gene expansion is a promising target for HD prevention ...