With the development of the newer agents, abiraterone acetate and enzalutamide, efforts have been made to better define the basis for response and resistance. This work can be carried out in cell ...

Currently, abiraterone acetate is being tested in a Phase III trial for men with progressive castration-resistant prostate cancer who are chemotherapy naive. A Phase III trial for patients ...

Meanwhile, in the active comparator arm, patients will receive abiraterone acetate plus prednisone. In the Phase III MAGNITUDE trial, BRCA-positive patients treated with the combination Akeega ...

UK-based pharmaceutical company AstraZeneca has reported positive results from its Phase III CAPItello-281 trial, which evaluated Truqap combined with abiraterone and androgen deprivation therapy ...

which may warrant concomitant glucocorticoid replacement with long-term administration of abiraterone acetate. In another Phase I trial, Ryan and colleagues performed a dose-escalation study in 33 ...

NICE is unable to make a recommendation about the use in the NHS of niraparib with abiraterone acetate and prednisone for untreated hormone-relapsed metastatic prostate cancer in adults. This is ...

As surgery wouldn’t have been effective, Alfred enrolled in the Cancer Research UK-funded STAMPEDE trial, which tested the drug abiraterone. Alfred responded well to the treatment and his cancer ...

Researchers will use a lipidomic biomarker test to select patients with a poor prognosis who may benefit from an investigational combination therapy.

In the final analysis of data from the "PROfound" trial, researchers found that olaparib blocked prostate cancer growth more effectively than the modern targeted hormone treatments abiraterone and ...

Evan Y. Yu, MD, discusses the therapeutic options for metastatic castration-resistant prostate cancer (mCRPC) included in the National Comprehensive Cancer Network (NCCN) guidelines, such as ...