These newer drugs have a broader antifungal spectrum with activity against resistant fungi. Itraconazole is a fungistatic oral agent which slows fungal cell growth by inhibiting cytochrome P450 ...

"For decades, clinicians have relied on a handful of antifungal classes, with few mechanisms of action and significant limitations due to spectrum of activity, drug toxicities, or drug-drug ...

1,2 Understanding antifungal drug resistance is fundamental to developing effective prophylactic and therapeutic strategies to avoid the problems that are now being encountered with resistant fungi.

Amphotericin B is a widely used, broad-spectrum polyene antifungal, but its use is associated with kidney ... The outbreak is notable, because it is the first in Africa—where much of the disease ...

Anti-Fungal Therapy Market. The global anti-fungal therapy market is set to experience significant growth, with a projected ...

This article examines three distinct clinical situations where liposomal amphotericin B, a broad-spectrum antifungal agent ... B at 3 mg/kg/day was added because of its broad spectrum of activity ...