Understanding the intricate interactions between antibodies and antigens is an important step in drug development. However, the complex and vast nature of the data presents significant challenges in ...

The bound structures of antibody and antigen are derived from the same protein complex PDB, and the unbound structures of antibody and antigen are derived from other proteins that can align with the ...

Uniform protein labeling in intact tissues is a challenge. An approach that allows antibodies to seep within organs could ...

In addition, even antigen-naïve animals often express “natural antibodies ... thus permitting the construction of immune complexes for presentation before the development of acquired ...

YUMAB’s antibody discovery and development ... but great effort is being channeled into targeting more complex and difficult antigens, such as multimembrane-spanning receptors, receptor ...

Repetitive HIV vaccinations can lead the body to produce antibodies targeting the immune complexes already bound to the virus ...

Determining how to predict the antibody-antigen interactions was the biggest challenge. The researchers focused on the ...

Bispecific antibodies (bispecifics) can simultaneously target two distinct antigens or epitopes ... makes bispecifics effective in treating complex diseases, including certain cancers, autoimmune ...

"These anti-immune complex antibodies have not been studied in ... some of the antibodies were not binding directly to the HIV viral antigen, but to immune molecules on its surface.