Advances in our understanding of autoimmunity and tumour immunity have led to improvements in immunotherapy for these diseases. Ironically, effective tumour immunity requires the induction of the ...
In Berlin, researchers and clinicians were brought together again to share common interests in defining new therapeutic approaches to transplantation and autoimmunity. This meeting report focuses ...
Immune dysregulation is often defined as an immune response that is directed against one of the body’s own tissues, cells or molecules (e.g. autoimmunity) or against an innocuous foreign molecule that ...
Aly et al. [17] provided evidence that risk for islet autoimmunity drastically increased in DR3/4-DQ2/DQ8 siblings who shared both HLA haplotypes identical by descent with their diabetic proband ...
Science is full of ideas that have been proven wrong. Up until the 1950s, one prevailing view among scientists was that the body could not produce antibodies against itself. This concept, known as ...
Building on its traditional strengths in immunology and autoimmunity, the Center faculty has developed programs in translational human genetics, focusing on the immunogenetic basis of autoimmune ...
Teplizumab’s approval is just the first critically important step toward screening, early detection, and prevention of autoimmune diseases. These paradigm shifts will, with time, change the way ...