Researchers have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other antigens within them ...
“What they’ve done is make a more intelligent CAR T cell,” says Michael Z. Lin, a bioengineer at Stanford who was not involved in either study, who describes Lim’s paper as “great.” While Lim and his ...
Yescarta – a CD19-directed genetically modified autologous T-cell immunotherapy investigated in the ZUMA-1 trial – is the first chimeric antigen receptor (CAR) T-cell therapy recommended for ...
The CAR-T process involves several steps where a patient’s own white blood cells are harvested, genetically modified, and reinjected to fight blood cancer. Costs to the healthcare system are ...
The study, published today in the journal Nature Immunology, focused on chimeric antigen receptor (CAR)-T cells, an effective therapy against cancer, especially leukemia and lymphoma.
A study published in Science Advances shares new insights into how two of the most common types of chimeric antigen receptor (CAR) T cells kill cancer. Investigators from Baylor College of ...
After injection, the CAR-T cells got to work, multiplying and seeking out the target B cells, including the pathogenic ones underlying the autoimmune conditions. This persisted for a few weeks ...