In each cell cycle, the integrity of genetic and epigenetic ... Thus, refined mechanisms have evolved to ensure stability through the concerted transmission of genetic and epigenetic information ...

A "pocket" on the protein cyclin B is responsible for ensuring that the steps of cell division take place in the correct order. Two studies by researchers at the University of Konstanz investigated ...

The cell must also pass through a series of checkpoints that ensure conditions are favorable for division. In order to move from one phase of its life cycle to the next, a cell must pass through ...

Initiation must be triggered at the appropriate time in the cell cycle at many hundreds or thousands of separate sites (origins of DNA replication) in the parental chromosomes. However, initiation ...

"This means that proteins are being regulated at multiple levels to ensure the cell cycle occurs as programmed." The research team used fluorescence microscopy to track around 4,000 proteins in ...