Denatonium is the most bitter chemical compound known, with bitterness thresholds of 0.05 ppm for the benzoate and 0.01 ppm for the saccharide. It was discovered by Macfarlan Smith, a Johnson Matthey ...

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For as long as I can remember, I’ve always been a nail-biter—until now, thanks to the best nail-biting polishes, which, for the uninitiated, use a foul flavor to make nibbling a little less appealing.