Dystrophin is part of a protein complex linking the cytoskeleton of muscle fibers to the surrounding connective tissue (basal lamina). It’s a long protein with numerous redundant coils (purple balls), ...

such as dystrophin. This critical protein maintains muscle structure and function, but its absence or deficiency spells trouble. While some forms of MD, like Duchenne Muscular Dystrophy ...

Dystrophin and DGC are also lost in Duchenne muscular dystrophy. The loss of dystrophin and damage to the DGC appear to be key players in the development of both cancer wasting and muscular dystrophy.

SAST and syntrophin were highly associated with purified microtubules and microtubule-associated proteins, whereas utrophin and dystrophin were only partially associated with microtubules.