Peak fluconazole concentrations of 16–32 µg/ml were reached in all patients. Mean concentrations above 16 µg/ml were maintained for 17.0 ± 8.0 h at an ultrafiltration rate of 1,000 ml/h, ...

Causes other than fluconazole prophylaxis that might have ... The Unit's policy on empiric antibiotic use, particularly cephalosporin use, did not vary during the study period.