Systemic infections: doses of up to 400mg ... when given within 24hrs after fluconazole. Caution with amiodarone (esp. with high-dose fluconazole), other drugs metabolized by CYP2C9, CYP2C19 ...

DURHAM, N.C. -- For the roughly 150,000 patients with AIDS who come down with a life-threatening infection called fungal meningitis each year, there aren’t many options. In many parts of the world ...