By thoroughly analyzing GBM glycolysis, this study seeks to provide a theoretical basis for developing novel therapeutic targets and improving clinical outcomes for GBM patients. 2 The role of lactate ...
It serves to build a new cell, (i) fueling building blocks for the synthesis of proteins, nucleic acids, and membranes, and (ii) producing energy through glycolysis. Cyclin-dependent kinases (Cdks) ...
Abstract: A general reaction–diffusion system modelling glycolysis is investigated. The parameter regions for the stability and instability of the unique constant steady-state solution is derived, and ...
A critical factor in this devastating disease is the metabolic reprogramming exhibited by cancer cells, particularly the preference for aerobic glycolysis over oxidative phosphorylation ...
Glycolysis usually occurs in the cytoplasm during ischemia. The mechanism of cerebral ischemia-induced hyperglycemia was investigated. Methods: Both non-fasting young (2-month-old) and aged ...
This important study investigates the molecular mechanisms underpinning how the tumor necrosis factor alpha-induced protein (TIPE) regulates aerobic glycolysis to promote tumor growth in melanoma.