Researchers have made a major breakthrough in our understanding of Huntington's disease. This genetic disorder has long been known to be caused .. | Genetics And Genomics ...

In everyone, the genetic alphabet that spells out the Huntingtin gene contains a repeat of the "letters" CAG ‒ typically as many as 25 times in a row. But people who inherit the disease are born with ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating hereditary disorder that strikes in the prime of life.

and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington's disease leads to the death of brain cells. The findings change the ...

and McLean Hospital have discovered a surprising mechanism by which the inherited genetic mutation known to cause Huntington’s disease leads to the death of brain cells. The findings change the ...

Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

is littered with a sort of genetic stutter — repeats of a sequence of three DNA letters: “C-A-G.” A hallmark of Huntington’s disease is that the number of CAG repeats a person has ...

Huntington’s disease is horrible ... But Huntington’s second, self-preserving, oddity is that unlike most genetic disorders it rarely manifests until well into adulthood, giving plenty ...

mutating the genetic code and ultimately rendering viral genes useless. But in the case of people with Huntington's disease, some of these helper proteins may be attacking and destabilizing not ...

which could help delay or even prevent the disease. Previous genetic studies of Huntington’s, including studies by Vanessa Wheeler and Ricardo Mouro Pinto at Massachusetts General Hospital ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating hereditary ... of the brain to break down and die. The genetic mutation linked to Huntington's has ...