Medically reviewed by Jonathan B. Jassey, DO High ammonia levels are toxic and cause symptoms such as headache, confusion, ...
Sandra A. Banta-Wright, MN, RNC, NNP; Robert D. Steiner, MD Neonates with profound and prolonged hyperammonemia with coma due to urea cycle defect will have had a neurological insult to the brain ...
Beyond UCD, the company plans to initiate a phase 1b trial in patients with cirrhosis and hyperammonemia. In addition to SYNB1020, SYNB1618, a candidate probiotic to treat phenylketonuria (PKU ...
It will also compare neonates with and without hyperammonemia to identify differences in clinical characteristics, including gestational age, mode of delivery, comorbidities, and clinical status.