infusion over 12 h Day 2 Etoposide 100 mg/m 2 by iv. infusion over 30 min Actinomycin D 0.5 mg iv. bolus Folinic acid rescue 15 mg orally every 12 h for four doses (starting 24 h after commencing ...

If continuous IV infusion is needed, begin immediately after bolus administration. Initial infusion rate: 10mg/h; may increase in 5mg/h increments up to 15mg/h. May be maintained for up to 24 hours.

it is possible to administer 5-FU solely through continuous infusion, minus the bolus (quick-delivery via intravenous push) ...