研究选择LPS(TLR4配体)深入探讨分子机制,发现LPS处理后小胶质细胞系BV-2中自噬受抑制,而在骨髓来源的巨噬细胞(BMDM)及小鼠巨噬细胞系Raw264.7 ...
Toll-like receptor (TLR) recognition of microbial compounds initiates signalling cascades that activate inflammatory and immune-response genes. A recent report in Nature shows that the nuclear ...