New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead to better treatments.

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the brain to ...

Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

Symptoms of Huntington's disease appear late in life. Research reveals how DNA repeats grow toxic over time, explaining the ...

Huntington’s disease is horrible ... of triplets in the expansion to increase slowly throughout a person’s life. That such expansion happens was noticed in the 1990s, but not widely thought ...

A recent study published in Cell reveals that the repeated DNA sequence that leads to Huntington’s disease (HD) expands ...

Huntington's disease is a hereditary disorder caused by a genetic mutation in the HTT gene, leading to progressive brain cell damage, affecting movement, cognition, and behavior, with no current cure.

Huntington's disease kills a population of cells called ... These symptoms typically begin in mid-life and then progress over 10 to 20 years to more severe cognitive problems and difficulty ...

In Huntington's disease, the mutant huntingtin gene (HTT ... and physical injury from falls reduce life expectancy to around twenty years after symptoms begin. There is no cure for HD, and ...

Beta blockers were associated with later appearance of motor symptoms and slower symptom worsening, but an outside expert ...

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately 20 years before a clinical motor diagnosis in people with Huntington's disease, ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...