Data from this study, taken together with three other randomized, double-blind studies comparing candesartan and losartan, demonstrate superior antihypertensive efficacy of candesartan over losartan.

Two classes of antihypertensives target angiotensin ... (lisinopril and hydrochlorothiazide); ARBs and diuretics (losartan or valsartan and hydrochlorothiazide); and diuretics and diuretics ...

For example, the Losartan Intervention For Endpoint reduction ... Similarly, in the Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT), 5 in which drugs from ...

An even larger U.S. study showed similar adjusted hazard ratios of 0.70 to 0.75 for ARBs versus other antihypertensive classes, which appeared to be driven by a reduction with losartan.

CLAIM Study Investigators: Amin Abdelghany, MD, Panama City, FL; Allen B. Adolphe, MD, Albuquerque, NM; J. Richard Allison, MD, Columbia, SC; Norse Bear, MD, Lakewood ...