Following release from hepatocytes, each merozoite infects an erythrocyte, thus triggering the bloodstream stage of infection and the pathology that is associated with malaria. Earlier research ...

Models of malaria and leptospirosis have been used to show that common hemodynamic changes in tropical disease include decreased systemic vascular resistance, increased cardiac output and ...

Cerebral malaria (CM) is a complex of syndromes relating to the presence of Plasmodium falciparum-infected erythrocytes sequestering in the brain microvasculature. The mechanisms of pathology are ...

1 Vascular Immunology Unit, Department of Pathology, Sydney Medical School, The University of Sydney, Camperdown NSW 2042, Australia. Cerebral malaria (CM) is a complex of syndromes relating to ...

"The way in which PfEMP1 functions and how it is neutralized by human antibodies are increasingly being uncovered on a structural level and are essential for understanding malaria pathology and ...

WHO disease outbreak news report1 on malaria underscores the challenges posed in DR Congo and neighbouring regions.2 The update identifies acute respiratory infections complicated by malaria, with 891 ...

A decade and a half later, he was back on campus—this time with malaria as his designated target. The disease persists as one of the developing world’s deadliest, in part because of the difficulty of ...

reduced mortality from experimental cerebral malaria in mice. The research, published in PNAS and funded by the Medical Research Council, also shows that animals treated with inflammasome inhibitors ...