Oxidative stress plays a critical role in the pathogenesis of upper and lower respiratory tract diseases, such as chronic rhinosinusitis with nasal polyps (CRSwNP), allergic rhinitis (AR), and asthma ...

All COX2 inhibitors undergo oxidative drug metabolism by cytochrome P450 (CYP) enzymes. Celecoxib has ... extensive records of papers on cyclo-oxygenase-2 and cyclo-oxygenase-2 inhibitors dating ...