编者按：在药物研发领域，靶向蛋白降解（Targeted Protein Degradation）技术近年来快速发展，正在开创现代药物研发的新篇章。这项技术能够针对传统小分子抑制剂或抗体药物难以靶向的蛋白发挥作用，让过去被视为“不可成药”的靶点变得可及 ...

Andy Extance charts how research into revolutionary targeted protein degradation therapies is moving from serendipity to ...

The onset or progression of many refractory diseases, including neurodegenerative disorders and cancers, is caused by the accumulation of proteins. Targeted protein degradation (TPD) has emerged ...

Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell ...

Scientists have used deep learning to design new proteins that bind to complexes involving other small molecules like ...

Girolline, a compound extracted from the sea sponge Pseudaxinyssa cantharella, has been investigated for possible antitumor ...

In a report released today, Srikripa Devarakonda from Truist Financial assigned a Buy rating to Kymera Therapeutics (KYMR – Research Report).

In a report released today, Tazeen Ahmad from Bank of America Securities maintained a Hold rating on Kymera Therapeutics (KYMR – Research ...

Learn about Nurix Therapeutics (NRIX) focusing on protein degradation in cancer treatment, with promising early-stage data ...

Cambridge, UK, 13 January 2025 – Amphista Therapeutics, a leader in the discovery of next-generation, Targeted, Protein ...