Bacterial protein glycosylation is a critical post-translational modification that affects various cellular processes, including protein stability, immune evasion, and interaction with host organisms.

Analytical Research Center for Organic and Biological Molecules, State Key Laboratory of Drug Research, Carbohydrate-Based Drug Research Center, Shanghai Institute of Materia Medica, Chinese Academy ...

A recent study has uncovered how specific genetic mutations in α2δ-1 and α2δ-3 proteins linked to autism spectrum disorders (ASD) alter neuronal functionality. These mutations significantly reduce the ...

Protein glycosylation is a fundamental biological process that regulates various cellular functions, yet its study has been hampered by the complexity and low abundance of glycoproteins. In a ...

Congenital disorders of glycosylation (CDG) are a group of hereditary diseases characterised by deficiency of enzymes involved in proteins glycosylation. We describe the clinical case of a neonate ...

This enables plants, in contrast to bacterial hosts, to synthesize and fold complex human proteins correctly (Tschofen et al., 2016), as well as to perform the majority of posttranslational ...

2012). Recombinant hEPO was recovered from culture supernatant by precipitation with trichlorocetic acid as described before (Büttner-Mainik et al., 2011). Protein pellets recovered from culture ...

The genomes of other chlorella virus isolates are probably co-linear with PBCV-1 and appear to share many, but not all, genes. This suggests that the entire "gene pool" of this genus exceeds the 375 ...

lumc.nl Objective To determine whether anticitrullinated protein antibodies (ACPA) exhibit specific changes in Fc glycosylation prior to the onset of arthritis. Methods Serum samples of patients with ...