A team of scientists at the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg and the University of ...

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site ...

美国国家癌症研究所的 Yun-Xing Wang 教授在 Nature在线发表了两篇题为「The conformational space of RNase P RNA in solution」（图 1）和「Determining structures of RNA ...

Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.

In cells, they ensure the transfer of genetic information and regulate the activity of genes. Some even act as catalysts, ...

and RNA stability, localization, structure and translation efficiency. Alternative polyadenylation (APA) generates mRNAs with varying 3′ termini. It is regulated by variation in the ...

The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.

No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...

In plants, secondary and tertiary RNA structures, such as G-quadruplexes, play vital roles, especially under conditions favoring structural stability, such as low temperatures. Despite the ...

The integration of high-throughput sequencing technologies, bioinformatics tools, and structural biology approaches will provide a more comprehensive understanding of the complex interplay between RNA ...

Researchers have determined the 3D structure of SAMURI, an artificial ribozyme that precisely modifies RNA. Using ...