Stem-cell differentiation is the process by which a more specialised cell is formed from a stem cell, leading to loss of some of the stem cell's developmental potential. Stem-cell differentiation ...
“The idea that you could use electrical fields and 3D mechanical properties to impact stem cells without having to use different kinds of biomolecules or expensive growth factors to drive ...
Our longterm goals are to understand the mechanisms regulating the growth, differentiation and self-renewal of skeletal muscle satellite cells for eventual use in cell-based gene therapy approaches.
The authors examine the role of Numb, a Notch inhibitor, in intestinal stem cell self-renewal in Drosophila during homeostasis and regeneration. This is an important study providing evidence of a Numb ...