通过线粒体转移,癌细胞不仅实现了对T细胞功能的精确抑制,还为其免疫逃逸增加了一道屏障。该研究进一步指出,这种机制与免疫治疗效果不佳密切相关,尤其是在携带大量mtDNA突变的患者中,免疫检查点抑制剂的疗效显著降低。
Research led by the Chiba Cancer Center Research Institute in Japan has discovered a surprising way cancer evades the immune ...
A faulty cancer gene helps tumors evade immunity ... (HCC), and compelling data supporting the role of beta-catenin in immune evasion. They suggest this work will be of special interest to ...
Immune evasion in ovarian tumors involves a complex array of immune suppressive factors and cells that effectively halt the generation and clonal expansion of antitumor immunity. Genetic changes ...
A new study from Oregon Health & Science University has uncovered how small molecules within bacteria interact with proteins, ...
Demonstrate how advanced image analysis software can be applied to discover cell types, populations and morphological and spatial context. Discuss how whole slide mIF based immune profiling through ...
1 Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA 2 The Sidney Kimmel Cancer Center, Johns Hopkins University School of Medicine, Baltimore, MD, USA 3 The ...
KSHV can be found in connection with many types of cancer, especially those with ... “This suggests the virus may be using LANA as an immune evasion tactic, preventing the immune system from ...
(“Purple Biotech” or the “Company”) (NASDAQ/TASE: PPBT), a clinical-stage company developing first-in-class therapies that overcome tumor immune evasion and drug resistance, today ...