To the best of our knowledge, this is the first study aimed at identifying factors predicting primary NHA resistance. In our experience of everyday clinical practice in an unselected CRPC ...

NICE is unable to make a recommendation about the use in the NHS of niraparib with abiraterone acetate and prednisone for untreated hormone-relapsed metastatic prostate cancer in adults. This is ...

The recommended Phase II dose of abiraterone acetate is 1000 mg orally daily in combination with prednisone 5 mg twice daily. Side effects are minimal and mostly associated with secondary ...