22, 2025 — Pathogen-fighting immune cells called tissue-resident memory CD8 T cells (TRM cells) go through a surprising transformation -- and relocation -- as they fight infections in the small ...

上海交通大学医学院附属仁济医院-上海市肿瘤研究所覃文新/王存团队联合复旦大学附属中山医院高强教授团队等在《Cancer Cell》上发表了题为“Targeting the immune privilege of tumor-initiating ...

while microglia displayed increases in inflammatory markers like Ildr2 and Ccl4. Glial cells, such as astrocytes and oligodendrocytes, displayed reduced expression of support-related genes.

Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.

eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

为了验证颗粒酶K在疾病进展中的作用，研究团队构建了小鼠哮喘模型。结果表明，随着气道炎症的复发次数增加，颗粒酶K的表达水平也随之上升。当通过基因敲除或药理学方法抑制颗粒酶K活性时，小鼠的呼吸道炎症明显减轻，肺功能得到改善。使用颗粒酶K特异性抑制剂PPA ...

Cell biology is the discipline of biological sciences that studies the structure, physiology, growth, reproduction and death of cells. Research in cell biology uses microscopic and molecular tools ...

窗含西岭千秋雪，门泊东吴万里船。在这个银装素裹的冬季，让小编带大家一起回顾一下2024年12月Cell Press期刊所发布的精彩封面！*以下所有内容译自英文，仅供参考，请以英文原文为准。以实际出版日期先后排序。Cell Metabolism出版时间 ...

Thus, in this review, we summarize our current understanding of the interaction between nociceptors and, specifically, the myeloid cells of the innate immune system, while pointing out some of the ...

These regulators are known as MYB, HDAC2, and FOXA2 and when they were suppressed in colon cancer cells, the cells switched back to a normal-like state, removing the cancer threat without ...