This important study provides solid evidence to support the anti-tumor potential of citalopram, originally an anti-depression drug, in hepatocellular carcinoma (HCC). In addition to their previous ...

Cellular immunity is a protective immune process that involves the activation of phagocytes, antigen-sensitized cytotoxic T cells and the release of cytokines and chemokines in response to antigen.

Jan. 28, 2025 — The latest findings on the interaction between cell death and cellular senescence in cancer and their pathophysiological significance have been ... Keeping the Steps of Cell ...

Induces potent and long-lasting immune responses to defined antigens or whole pathogens (particles), mainly through the ...

Pharmacologic or genetic inhibition of PGAM inhibited Treg differentiation and shifted CD4 T cells toward a pro-inflammatory, Th17-like state. Mechanistically, we found that PGAM regulates Treg ...

Talimogene laherparepvec (T-VEC) demonstrates efficacy in cutaneous BCC, enhancing resectability and altering immune cell ...

1 contribute to evasion of CD8 + T cell responses. Mutations occurring in T cell epitope hotspots in the viral spike protein and in a highly conserved site in the viral nucleocapsid suggest that T ...

Preliminary studies showed a decrease in cellular infiltration with normalisation of keratinocyte differentiation in the skin ... There is increasing evidence to support a role of T cells—CD4+, CD8+, ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.

Secondly, Stoloff considers the cuts of T-shirts by asking a few questions, such as: “Are you wearing this in the summer or layered in the winter under a blazer? Do you want a boxy, boy fit or a ...

Got a bad cell phone signal? Without a stable connection ... of your friends' Instagram stories you'll miss out on). But don't panic: there's probably a simple solution. In fact, whether you ...

Mechanical Engineering, Faculty of Engineering and Physical Sciences, University of Southampton, Southampton SO17 1BJ, U.K. Perioperative and Critical Care Theme, NIHR Southampton Biomedical Research ...