Our cell biology researchers collaborate with molecular ... They include the cytoskeleton, a dynamic internal protein network that gives cells their shape and their ability to move — a key function ...
Certain microbes exploit the relationship with stem cells; transform their niches to gain an extreme degree of self-renewal potentials and subsequent malignant properties, thus contributing to cancer ...
Jan. 15, 2025 — While most known types of DNA damage are fixed by our cells' in-house DNA repair mechanisms, some forms of DNA damage evade repair and can persist for many years, new research shows.
Tumor molecular pathology is an evolving field dedicated to uncovering the molecular underpinnings of cancer development and progression. This discipline ...
An international research team led by the University of California, Irvine has discovered a new type of skeletal tissue that offers great potential for advancing regenerative medicine and tissue ...
Professor Kwang-Hyun Cho remarked, "The fact that cancer cells can be converted back to normal cells is an astonishing phenomenon. This study proves that such reversion can be systematically induced." ...
Tuspetinib (TUS) is a well-tolerated, once daily, oral kinase inhibitor in clinical development for treatment of acute myeloid leukemia (AML). Nonclinical studies show that TUS targets key prosurvival ...
Breast luminal epithelial cells are the hotspots of aging-associated changes, which prime aged epithelia for oncogenic gene activation and may explain individual differences in breast cancer ...
the common goal of current cancer therapies is to eliminate cancer cells. This approach, however, faces fundamental limitations, including cancer cells developing resistance and returning ...