The paper presents a streamlined new approach for functional validation of genes known to underlie fragile bone disorders in a relatively high throughput, using CRISPR-mediated knockouts and a number ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. AUTS2 syndrome patients often exhibit ...

CRISPR-Cas9 is one of the biggest discoveries of the 21st century. Since it was developed in 2012, this gene-editing tool has revolutionized biology research, making it easier to study disease and ...

reverse primer: GCCACCGAGGAAGTAGTTCA. Human endogenous reference gene GAPDH (B661104; Sangon Biotech). RNAiso Blood (9113; Takara) was used to obtain total RNA from the blood. The HiScript III 1st ...

Oprah is a fan of the brand, too. Perfect for mature skin, Laura Geller’s hydrating primer comes in a rich cream-to-gel formula that’s super moisturizing yet lightweight. It’s ideal for ...

Respiratory illnesses saw a surge in China in the week to 22 December, China’s disease control authority said on 27 December. Known pathogens like influenza, respiratory syncytial virus (RSV ...