Protein modifications are key to cell survival because they ensure they do what they are supposed to do in a healthy system.

Proliferating animal cells maintain a stable size distribution over generations despite fluctuations in cell growth and division size. Previously, we showed that cell size control involves both cell ...

The role of phosphorylation in regulating protein function and cellular signaling is perhaps one of the most important questions in biology. Classical methods like mobility-shift assays allow ...

Cells exit their cell cycle in response to environmental cues. Recently, a novel class of CDK inhibitory proteins has been described that putatively links the cell cycle and stress responses.

Mitosis, the fundamental process by which cells divide, ensures the accurate distribution of genetic material to daughter ...

Understanding bacterial growth mechanisms can potentially help uncover novel drug targets that are crucial for maintaining cellular viability, particularly for bacterial pathogens. In this important ...

Discover how the synergy between AI and cell-free systems is driving a new era in biopharma innovation, accelerating drug ...

Esophageal squamous cell carcinoma (ESCC) is a severe health threat, being a predominant subtype of esophageal cancer and ...

A study identifies promising compounds targeting PI3Kα for the treatment of triple-negative breast cancer, offering new ...

The two proteins, KNL2 and CENP-C, are crucial for correctly separating chromosomes during cell division. They dock precisely onto the centromeric DNA, analogous to the "lock and key principle." ...

Each night, our brains execute a "wash and rinse" routine that clears away harmful protein waste linked to neurodegenerative ...