CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing ...

CRISPR Therapeutics' stock decline is likely influenced by Editas Medicine's struggles, but CRISPR remains a distinct and stronger company with a promising long-term outlook. CRISPR's strategic ...

CRISPR-Cas9 is one of the biggest discoveries of the 21st century. Since it was developed in 2012, this gene-editing tool has revolutionized biology research, making it easier to study disease and ...

ZUG, Switzerland and BOSTON, Jan. 13, 2025 (GLOBE NEWSWIRE) -- CRISPR Therapeutics (Nasdaq: CRSP), a biopharmaceutical company focused on creating transformative gene-based medicines for serious ...

该研究对用于 CRISPR 基因编辑治疗的 Cas 核酸酶 SaCas9 和 AsCas12a 进行了理性工程化改造，设计出了具有最小化免疫原性的 SaCas9 和 AsCas12a 突变体。

Bring up germline editing, and most scientists cringe. The idea behind the notorious CRISPR-baby scandal, editing reproductive cells or embryos tinkers with DNA far beyond just the patient—any changes ...

Get Instant Summarized Text (Gist) CRISPR nucleases, Cas9 and Cas12, have been engineered to evade immune detection, addressing a key challenge in CRISPR-based therapies. By identifying and ...

Heidi Schwarzenbach的论文“Impact of exosomal and cell-free circRNAs on cancer drug resistant”发表在ExRNA杂志上，综述了多种靶向多种miRNA的circRNAs在耐药中的作用。 作者综述了细胞外环状RNA在癌症中的调控网络及其对癌症耐药的影响。为了传播恶性肿瘤，环状RNA作为无细胞分子 ...

作者综述了细胞外环状rna在癌症中的调控网络及其对癌症耐药的影响。为了传播恶性肿瘤，环状rna作为无细胞分子或外泌体（小囊泡）在血液循环中穿梭，在那里它们被运送到各种细胞。发表在《ExRNA》杂志上的circRNAs网络有潜力被用作癌症治疗策略的治疗靶点或 ...

Then Crispr came along—the elegant enzymatic apparatus that allows delivery of DNA scissors to a specific target in the genome. In December 2023, the FDA approved the first Crispr-based therapy ...

A specific and sensitive detection assay for BCoV is critical to the early-stage disease prevention and control. Methods: We established a specific, sensitive, and stable assay for BCoV nucleic acid ...