Scientists from A*STAR Genome Institute of Singapore (A*STAR GIS) have uncovered that a key enzyme—P4HA1 prolyl hydroxylase, ...
Instead of the enzyme mechanism described in biochemistry text-books, hen lysozyme hydrolysis was postulated to occur by a ring-opening mechanism based on substrate interactions defined by the active ...
Researchers from the Manchester Institute of Biotechnology and the Department of Chemistry at The University of Manchester ...
A new study has uncovered a critical role for the enzyme Glucose-6-phosphatase 2 (G6PC2) in regulating blood sugar levels.
With an interdisciplinary approach, Yang’s lab is able to reprogram and reinvent nature’s biosynthetic machinery to catalyze ...
Compounds that enhance enzyme activity show promise for cellular rejuvenation and treating age-related diseases. However, ...
Because of their large size, complex design and changing shapes, NRPS enzymes are highly dynamic and difficult to study.
A research team at the University of Freiburg led by biochemist Prof. Dr. Oliver Einsle has discovered how the ‘Shethna protein II’ protects the nitrogen-fixing enzyme nitrogenase from damage. The ...
Structural biology incorporates the principles of molecular biology, biochemistry and biophysics. The enzyme nitrogenase ‘fixes’ nitrogen gas to form bioavailable ammonia, a vital process for ...
A recent research conducted by members of Qatar University’s (QU) Health Sector delineated the mechanism that a mutation in a gene encoding for an important protein can lead ...