Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...
A meaningful rank of NSAIDs in terms of inhibition of COX should take into account the complexities inherent in biochemical systems, including the mechanism of catalysis of the endogenous substrate.
The State Key Laboratory of Molecular Engineering of Polymers and Department of Macromolecular Science, Fudan University, Shanghai 200438, P. R China ...
Enzyme production is a vital pillar of microbial biorefineries, as enzymes play a crucial role in the breakdown of feedstocks and the catalysis of bioproduction ... These include limitations in ...
Other NSAIDs do not have this effect. Cox-2 inhibitors are a newer form of prescription NSAID. As you might guess, they only affect Cox-2 enzymes and not Cox-1. Two of them -- Bextra and Vioxx ...