Researchers identified that the dominant B cell epitope of Lachnospiraceae flagellins and the utilization of the flagellin ...

A collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging ...

Determining antibody-epitope interactions is, at its most basic level, a structural biology problem. Determining what molecular interactions are present between an antibody and its antigen can define ...

In line with previous observations regarding the ability of AlphaFold to predict antibody structures and antigen binding, the results are mixed. While the authors are able to use AlphaFold to identify ...

A collaboration between the Ragon Institute and MIT’s Jameel Clinic has led to the development of MUNIS, a deep learning tool that significantly enhances T cell epitope prediction, accelerating ...

Malaria remains a significant global health challenge, causing over 600,000 deaths annually despite existing prevention and treatment measures. Current vaccines and monoclonal antibodies (mAbs) ...

This study introduces MUNIS, a deep learning tool that enhances T cell epitope prediction, crucial for accelerating vaccine ...

In this article, Cerba dives into CAR+ T-cell therapy, from patient treatment to solutions for minimal residual disease (MRD) ...

An exciting collaboration between the Ragon Institute and the Jameel Clinic at MIT has achieved a significant milestone in leveraging artificial intelligence (AI) to aid the development of T cell ...

Recently developed major histocompatibility complex (MHC) multimer technologies allow visualization and isolation of antigen-specific T cells. However, functional analysis and in vivo transfer of ...