肿瘤细胞的有氧糖酵解(Warburg 效应)与多种恶性行为相关,且乳酸衍生的组蛋白赖氨酸乳酸化是一种新型表观遗传修饰,可直接增加染色质内的基因转录。神经元前体细胞表达发育下调蛋白 4(NEDD4)作为 HECT 结构域 E3 连接酶家族的重要成员,在肿瘤细胞的多种过程中发挥关键作用,但 NEDD4 是否参与奥沙利铂和 5 - 氟尿嘧啶耐药的 HCC 发展尚不明确。
For patients with hepatitis B virus, alcohol is associated with dose-dependent increased risks for cirrhosis and hepatocellular carcinoma.
A new study shows that artificial intelligence (AI) can help doctors make better decisions when treating cancer. However, it also highlights challenges in how doctors and AI work together. The study ...
PRINCETON, N.J. - Bristol Myers Squibb (NYSE: BMY), a prominent pharmaceutical company with a market capitalization of nearly $120 billion and impressive gross profit margins of 76%, received a ...
Squibb announced that the Committee for Medicinal Products for Human Use of the European Medicines Agency has recommended ...