Scientists at Children's Medical Research Institute (CMRI) have solved a big mystery in cancer research—why cells die in ...

Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs) and collapsed replication forks. The fundamental reaction in homologous recombination is the exchange of ...

Exposure to radiation kills cells from the same tumors in different ways, and some are far more useful for saving lives than ...

Szmyd et al. show that DNA repair pathways impact whether cells with DNA lesions arrest in mitosis. The formation of homologous recombination-driven double Holliday junctions elicits mitotic cell ...

Homologous Recombination as a Major DNA Repair Pathway in Mammalian Cells Postdoctoral fellow Christine Richardson has demonstrated that mouse chromosomes 17 (red) and 14 (green) can be induced to ...

Scientists at Children’s Medical Research Institute (CMRI) have solved a remarkable puzzle in cancer research: why cells die ...

A study reveals that the way cancer cells die after radiotherapy depends on DNA repair methods. By blocking specific repair ...

How do we find out which protein works in a particular DNA repair pathway ... is consistently generated by Alu-mediated homologous recombination in acute myeloid leukemia. Proceedings of the ...

How do tumor cells die after radiotherapy- one of the most important type of cancer treatment- is one of the big mystery in ...

Published in Clinical Cancer Research, results of a VHIO-led study underscore the potential of the RAD51 biomarker in ...

Developed in-house by Serra’s laboratory, a test based on the detection of the RAD51 protein as a functional biomarker of ...