Dihydromyricetin (Dih), a naturally occurring flavonoid, has been identified to exert a protective effect against ischemia/reperfusion injury. However, the detailed mechanisms remain unclear. Here we ...

Brain injury resulting from hypoxia (oxygen deprivation) or ischemia (restricted blood flow) represents a major challenge in medical research and clinical ...

Hypoxia-driven gene and protein changes enhance ... These cells regulate key epithelial cell processes such as proliferation, metabolism, apoptosis, senescence and differentiation.

Australian researchers have identified an association between nocturnal hypoxia and neovascular age-related degeneration (nAMD). 1 Acting on this realization could prevent nAMD in some patients, ...

Granulocyte macrophage-colony stimulating factor (GM-CSF), tumour necrosis factor (TNF), hypoxia and bacterial endotoxins increase lifespan partly through upregulation of intracellular proteins ...

Pancreatic cancer has the worst survival rates among all solid tumor types, and its incidence is increasing. Hypoxic conditions that arise from an imbalance between increased oxygen consumption and an ...

Hypoxic biomarkers included oxygen saturation (SpO2), RBC indicators and the hypoxia-inducible factor 1 (HIF-1) signaling pathway. Carotid-femoral pulse wave velocity (cfPWV), a marker of arterial ...

Neural cell death has a pivotal role in both the development and pathophysiology of the nervous system. Two distinct modes of cell death—necrosis and apoptosis—are involved in pathological neuronal ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including ...