There are multiple sources of both endogenous and exogenous inflammation in CKD, including increased production and decreased clearance of proinflammatory cytokines, oxidative stress, metabolic ...

Yet, unlike most pioneering developers of new modalities, Bloom’s programs are underpinned by a century of clinical evidence of the efficacy of modulating the gut–immune–brain axis to treat ...

This review explores the relationship between gut microbiota, immune modulation, and cognitive decline, with a particular focus on the gut-brain axis. Research indicates that ... and the mitigation of ...

Traumatic brain injury can lead to profound downstream barriers to obtaining adequate nutrition from the diet.

However, this biological shape-shifting may worsen disease by crippling production of molecules like PSA that regulate the ...

Their study showed that the brain maintains a balance between molecular immune system signals that induce inflammation and ... liver, intestines, and so on. The vagus nerve plays a role in ...

People with the skin condition psoriasis often have invisible inflammation in the ... had higher numbers of certain types of immune cells in their small intestine, and the cells showed signs ...

Dr Matt Hepworth, Branch Lead for Immune ... and Inflammation, has been awarded a £2.8 million, 8-year Career Development Award (CDA) from the Wellcome Trust to conduct groundbreaking research into a ...

During fasting, neurons in the gut connected to the brain release chemical signals that bind to immune cells, telling them to leave the intestine ... chronic inflammation, high stress, or obesity.

Prior studies in both animals and humans have reported that neutrophils can cross the blood-brain barrier, and although these cells are not typically attracted to glioblastomas, they are recruited at ...