Mitochondrial permeability transition (mPT): A process where the inner mitochondrial membrane becomes permeable, allowing the passage of molecules and leading to potential cell death ...

Mitochondrial fusion is the physical merging of the outer and then the inner mitochondrial membranes of two originally distinct mitochondria. Mitochondrial division is the breaking apart of one ...

A source of energy in the form of adenosine triphosphate (ATP) is formed in the inner mitochondrial membrane by means of a sequence of reactions known as the respiratory chain. Involved in this ...

The Food and Drug Administration (FDA) has extended the review period for the New Drug Application (NDA) for elamipretide for the treatment of Barth syndrome, a rare genetic disorder.