ncl.ac.uk Background: In healthy subjects deep inspiration transiently dilates the airways, while many asthmatic subjects show bronchoconstriction by a mechanism which is incompletely understood. We ...

Changes in intrathoracic pressure are transmitted to the intrathoracic structures: namely the heart and pericardium, and the great arteries and veins. Spontaneous inspiration produces a negative ...

This results in the right heart relying more heavily on the decreased intrathoracic pressures during inspiration to fill, exaggerating the pressure change, which is measurable. To measure the ...

Intrathoracic obstruction is most ... Extrathoracic obstruction is increased during inspiration because of the effect of atmospheric pressure to compress the trachea below the site of obstruction.

This does not occur in restrictive cardiomyopathy. With inspiration, intrathoracic pressure decreases and the right ventricle fills. This causes the right ventricular pressure to increase ...

Negative-pressure pulmonary edema (NPPE) occurs when a large, negative intrathoracic pressure is generated against an obstructed upper airway, causing fluid to shift into the lung interstitium.

The residual microscopic disease that remains will lead to disease progression in the majority of patients. Delivery of hyperthermic intrathoracic chemotherapy at the time of surgery has been used to ...