Further, another 66% of the losartan group and 62% of the atenolol group received additional antihypertensive agents, mostly hydrochlorothiazide. This left approximately 11% in each group on study ...

losartan without a thiazide ... Thus to compare the antihypertensive efficacy of initial combination therapy vs. monotherapy, we prospectively evaluated the efficacy and safety of initial ...

The association between systolic blood pressure and all-cause mortality differs between frail and nonfrail individuals, highlighting uncertainties about the effectiveness of antihypertensive ...