In this valuable manuscript, authors ablate cerebellar oligodendrocytes during postnatal development and show that synchrony of calcium transients in Purkinje neurons and behaviours are affected even ...

The Human Microglia Atlas includes 91,716 brain immune cells covering six neurologic pathologies. It characterizes the signatures of nine populations and describes the expansion of GPNMB-high ...

Sphere of Influence. In iAssembloids, microglia (red) form projections (white arrows), while astrocytes (green) assume star shapes typically found in the brain. [Courtesy of Kampmann et al., 2025.] ...

Aerobic exercise may significantly reduce Alzheimer's disease markers, with studies showing up to 76% decreases in harmful ...

Xenon gas, currently used in medicine as an anesthetic and neuroprotective agent for treating brain injuries, showed ...

Morphological profiling allows accurate identification of cell types in dense iPSC-derived cultures, allowing its use for quality control and differentiation monitoring.

Subtle changes in the brain, detectable through advanced imaging, blood and spinal fluid analysis, happen approximately twenty years before a clinical motor diagnosis in people with Huntington's ...

A breakthrough study highlights Xenon gas as a potential game-changer in treating Alzheimer’s disease, demonstrating its ...

An icon of a desk calendar. An icon of a circle with a diagonal line across. An icon of a block arrow pointing to the right. An icon of a paper envelope. An icon of the Facebook "f" mark. An icon ...

Runner Graham Berry says raising awareness of motor neurone disease is a cause close to his heart. Megan and Jackie Wilson plan to run a mile a day in January to raise money for the MND Association.

The cylinder test and grid-walking test were performed to evaluate functional recovery. The potential molecular mechanisms of excitatory neuronal activation on microglia-mediated synaptic pruning ...