Hereby, we review the functions of microtubule cytoskeletal proteins in tumor cells and comprehensively examine the effects of microtubule-targeting agents on pancreatic carcinoma. In humans, ...

Mitosis orchestrates eukaryotic cell division, maintaining genetic fidelity and playing a key role in development, tissue homeostasis, and cancer progression.

Microtubules are cylindrical polymers composed ... formation of the mitotic spindle that segregates chromosomes during cell division and intracellular trafficking. During cell adhesion, integrins ...

Recently, a moonlighting function of Elongator has been identified in regulating the polarization of the microtubule cytoskeleton during asymmetric cell division. Elongator induces symmetry breaking ...

This article shows that a cytoplasmic dynein component is present at the kinetichore at least in prometaphase. Because the microtubules in the spindle are oriented with their minus ends at the pole ...

Microtubules guide the movement of the Bucky ... Solid-like structures in cells are mostly known from pathological contexts, such as prions, which irreversibly form and damage cells, causing ...

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Several faculty at the University of California, Davis, are among the recipients of presidential awards for excellence in STEM mentoring and research announced by the White House Jan. 13 and 14. The ...

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