A thermal stability-based proteomic analysis identifies cytoplasmic PEBP1 as a mediator of mitochondrial dysfunction-induced stress response, highlighting its potential role in cellular adaptation ...

The Midlands Integrative Biosciences Training Partnership is a BBSRC-funded doctoral training partnership between the universities of Warwick, Birmingham, Leicester, Aston, Harper Adams and Coventry.

These particles, called extracellular vesicles, are considered attractive vehicle models for new drug therapies. But until now, researchers haven't had the complete picture of how they work.

Organoid Research Center, Institute of Translational Medicine, Shanghai University, Shanghai 200444, People’s Republic of China National Center for Translational Medicine (Shanghai) SHU Branch, ...

independent of mitophagy and the lysosomal degradation of mitochondrial-derived vesicles (MDVs), allowing bidirectional crosstalk between these cell compartments, the dynamic regulation of organelle ...

This valuable study presents findings on the mode of action of MOTS-c (mitochondrial open reading frame from the twelve S rRNA type-c), and its impact on monocyte-derived macrophages. The authors ...

Numerous bioactive molecules are secreted by SKM and transported by extracellular vesicles (EVs), a novel class of mediators ... cells by transferring lipids (Aswad et al., 2014). Myotube-derived ...

In this chapter, we analyze the progress in the traffic of lipids between ER and mitochondria and we highlight the remaining unexplored questions. Most of the advances so far have been obtained in ...

From the Centers of Inflammation, Translational, and Clinical Lung Research (Y. Shao, Y. Sun, Y.L., F.S., C.D., C.J., K.X., X.J., X.Y.), Temple University, Lewis Katz ...