Tectonic Therapeutic has done well to advance its Fc-fusion protein candidate TX45 into a phase 2 study targeting patients ...

Tectonic Therapeutic said the findings support the design and population for Phase 2 APEX trial, which will test TX45 in ...

Shares of Tectonic Therapeutic, Inc. (NASDAQ: TECX) surged 40% following the announcement of encouraging interim data from a Phase 1b trial for its TX45 treatment in patients with Group 2 Pulmonary ...

Tectonic Therapeutic (TECX) announced positive interim data from the Phase 1b acute hemodynamic clinical trial of its lead product candidate, ...

TX45 improved both left ventricular function and pulmonary hemodynamics in patients with Group 2 Pulmonary Hypertension in Heart Failure with preserved Ejection Fraction (“PH-HFpEF”), supporting ...

Negative-pressure pulmonary edema (NPPE) occurs when a large, negative intrathoracic pressure is generated against an obstructed upper airway, causing fluid to shift into the lung interstitium.

(Lancet Diabetes & Endocrinology) Among patients with end-stage heart failure and low pulmonary capillary wedge pressure, left ventricular assist device therapy was associated with milder but ...

While pericytes are important regulators of capillary function and homeostasis, the lack of specific markers has hampered the investigation of pericyte biology. This study identifies Higd1b as a ...

According to the World Health Organization, hypertension (raised blood pressure) causes an estimated 7.5 million deaths worldwide, which is roughly 12.8% of all total deaths. Hypertension accounts ...

We used the nitrous oxide-body plethysmograph method to record the pulmonary capillary blood flow pulse and the phonocardiogram to determine the time of opening and closing of the pulmonary valve. The ...