Researchers have now uncovered the 3D structure of the RNA enzyme SAMURI. Their study provides insights into the development of ribozymes and the evolution of catalytically active RNA.
The current human tissue-based study provides convincing evidence correlating hippocampal expressions of RNA guanine-rich G-quadruplexes with aging and with Alzheimer's Disease presence and severity.
and RNA stability, localization, structure and translation efficiency. Alternative polyadenylation (APA) generates mRNAs with varying 3′ termini. It is regulated by variation in the ...
No large RNA structure database exists that correlates sequence with 3D topology. Successful protein-centric methods like AlphaFold remain unavailable for RNA, creating a critical gap in ...
The integration of high-throughput sequencing technologies, bioinformatics tools, and structural biology approaches will provide a more comprehensive understanding of the complex interplay between RNA ...