Collective cell migration is defined as the coordinated movement of multiple cells that retain cell–cell contacts while coordinating their actin dynamics and intracellular signalling.

Researchers find cell migration doesn't only rely on generating force. A professor of mechanical engineering and materials science found that groups of cells moved faster with lower force when ...

In mechanobiology, cells' forces have been considered fundamental to their enhanced function, including fast migration. But a group of researchers in the McKelvey School of Engineering at ...

Smooth muscle lacks the striated structure of skeletal muscle and instead consists of sheets or layers of smooth muscle cells. When stimulated by the autonomic nervous system to contract from the ...

The ECM (extracellular matrix) provides the microenvironmental niche sensed by resident vascular smooth muscle cells (VSMCs). Aging and disease are associated with dramatic changes in ECM composition ...

In atherosclerosis, the vascular smooth muscle cell (VSMC) contributes to vessel wall inflammation and lipoprotein retention, as well as to the formation of the fibrous cap that provides stability ...

Any residual thrombus which is still present after 36 hours will provoke smooth muscle cell migration into the area, with the production of new connective tissue which smooths out the surface and ...

Atherosclerosis risk is elevated in diabetic patients, but the underlying mechanism such as the involvement of macrophages remains unclear. Here, we investigated the underlying mechanism related to ...

Jan. 28, 2025 — A team of stem cell scientists have successfully used embryonic stem cell engineering to create a bi-paternal mouse -- a mouse with two male parents -- that lived until adulthood.