Researchers identify a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent ...

Oncolytic adenoviruses were designed to reach potent intratumoral T-cell activation via expression of bifunctional-T-cell engagers (MATEs). MATEs consist of a CD3 binding domain to bind T cells and a ...

As noted above, stellate cell activation is the central event in hepatic fibrosis. Activation consists of 2 major phases: (1) initiation (also called apreinflammatory stage) and (2) perpetuation ...

The direct-to-cell Starlink system in Southern California will deliver wireless emergency alerts and power SMS texting to 911 ...

Introduction: T cell activation requires T cell receptor (TCR) engagement by its specific ligand. This interaction initiates a series of proximal events including tyrosine phosphorylation of the CD3 ...

A recent Cell Reports paper by the Oxenius group (IMB) demonstrates a function of targeted centrosome inheritance during CD8+ ...

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1 Department of Medicine/Rheumatology, Thessaly University School of Medicine, Larisa, Greece 2 Elective Study Programme of Medical Biochemistry, Thessaly University School of Medicine, Larisa, Greece ...

An international team of UK and US scientists has discovered that the activity of macrophages—a type of white blood cell that ...

Methods: We characterized the soluble factors (SFs) released by activated human CAR-T and CAR-NK cells and assessed their role in BMC activation (BMCA). Results: We found that SFs from both activated, ...