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Impaired expression and regulation of CD39, an ectoenzyme key to immunotolerance maintenance, have been reported in Tregs and effector Th17-cells derived from AIH patients ... Low Galectin-9 in Tregs ...

In addition to essential physiological functions, BAs and their metabolites are also involved in the differentiation and functions of innate and adaptive immune cells such as macrophages (Macs), ...

The P/B ratio shows how a stock's market price compares to its book value. It helps gauge whether a stock is undervalued or overvalued relative to its net assets.

2 State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Peking University, Beijing, China 3 Department of Integration of Chinese and Western Medicine, School of ...

Pharmacologic or genetic inhibition of PGAM inhibited Treg differentiation and shifted CD4 T cells toward a pro-inflammatory, Th17-like state. Mechanistically, we found that PGAM regulates Treg ...